Pioneering Computational RNA Drug Discovery

Unlocking RNA’s Therapeutic Potential Through AI-Driven Computational Mastery

Darien Biodiscovery is a virtual CRO specializing in RNA-targeted drug discovery, structure modeling, and gigascale library design – no wet-lab work, no software licenses, just results.

Key Services Overview

RNA-Ligand Interaction Modeling
RNA Structure Prediction
RNA-Focused Chemical Libraries
RNA Therapeutic Optimization

Virtual screening, G-quadruplex targeting, Fragment-based drug design.

Secondary/tertiary modeling, folding dynamics, RNA-protein interfaces.

Gigascale libraries, non-enumerated spaces & generative AI-driven design.

siRNA/ASO, CRISPR guides design, aptamer design & optimization.

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Darien Biodiscovery – The Only Focused CRO for Computational RNA Drug Development

Join Hands with Darien – Decoding the New Era of RNA Medicine

Our Key Differentiators

RNA-Centric Expertise
Gigascale Power
Zero Overhead, Full IP

Exclusive focus on RNA targets – from viral elements to lncRNAs.

Screen >10B compounds with proprietary GPU/ML workflows.

No infrastructure costs. You own all data and designs.

Innovative Solutions

Developing advanced software for AI-aided drug design and discovery.

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A grey processor chip with the letters 'AI' prominently displayed in blue, set against a subtle background with faint outlines of a map.
Molecular Modeling

Our molecular modeling services enhance drug discovery through precise simulations and analyses, enabling companies to visualize and optimize potential drug candidates effectively and efficiently in their development processes.

A laptop displaying a graphical design program with multiple small thumbnails on the screen, placed on a desk. Two camera lenses are positioned on either side of the laptop, and the background shows a softly lit room with a large window.
A laptop displaying a graphical design program with multiple small thumbnails on the screen, placed on a desk. Two camera lenses are positioned on either side of the laptop, and the background shows a softly lit room with a large window.
Cheminformatics Services

We provide comprehensive cheminformatics services that support drug discovery efforts, utilizing data analysis and computational techniques to identify promising compounds and streamline the research process for our clients.